What it shows
What happens in your gut goes beyond digestion
The bacteria in your gut interact with digestion, mood, immunity, metabolism and the heart. GutID reports on those patterns so you and your practitioner can act on something specific.
Five physiological systems, read from one sample.
The five Gut Axes
Gut function is only the beginning
Your gut microbiome impacts more than just gut function. Through five Gut Axes - gastrointestinal, brain, immune, metabolic and heart - the molecules and immune signals it generates reach systems most people never connect to digestion, which is why one sample can speak to symptoms this varied. The Complete Microbiome Assessment reads across all of them. Core Gut Insights concentrates on gut function, for people whose concerns start and stay there.
Gut-Gastrointestinal Axis
Gut Function
In both reportsThe gut is where most host-microbe interaction actually happens. This section looks at bacterial patterns associated with digestion, barrier integrity and day-to-day digestive symptoms.
What this covers
- Small Intestinal Bacterial Overgrowth (SIBO)
- Inflammatory Bowel Disease (IBD)
- Bile Acid Metabolism
The guide lists what the gut microbiome contributes to here: digestion and fermentation of dietary substrates, nutrient absorption, maintenance of intestinal barrier integrity, regulation of mucosal immunity, production of microbial metabolites, and protection against pathogen colonization.
This is the area Core Gut Insights is built around, so if your concerns start and stay with digestion, that report covers it. It is in the Complete Microbiome Assessment too.
In practice: A flag means patterns reported more frequently in people with digestive dysfunction are present. Read it against symptoms, history and other results - never on its own.
Gut-Brain Axis
Mental Health
Complete Microbiome AssessmentGut and brain talk to each other constantly - through nerves, immune signaling and the molecules bacteria produce.
What this covers
- Mood Disorders
- Irritable Bowel Syndrome (IBS)
- Alzheimer's Disease (AD) Risk
- Parkinson's Disease (PD) Risk
The report evaluates bacterial species associated with neurological, behavioral and neuroimmune signaling, including pathways involving GABA, serotonin, dopamine and noradrenaline.
These findings do not diagnose neurological disease and are not evidence that a person has, or will develop, a particular disorder.
In practice: Useful where digestive and mood symptoms travel together, which is common and is usually handled as two separate problems.
Gut-Immune Axis
Immune Health
Complete Microbiome AssessmentRoughly 70 to 80% of the body's immune cells sit within or close to the gastrointestinal tract, so the bacteria there are in constant conversation with the immune system.
What this covers
- Lipopolysaccharide (LPS) Production
- Histamine Production
- Eczema and Atopic Dermatitis
The microbiome contributes to immune system maturation, development of immune tolerance, regulation of inflammatory responses, barrier integrity, host defense, and the balance of regulatory and pro-inflammatory pathways.
Alterations have been associated with allergic disease, autoimmune conditions and chronic inflammatory disorders.
In practice: Interpret alongside allergic history, autoimmune conditions and inflammatory markers.
Gut-Metabolism Axis
Metabolic Health
Complete Microbiome AssessmentGut bacteria sit inside the pathways that govern blood sugar, fat storage, appetite and inflammatory load.
What this covers
- Obesity
- Type 2 Diabetes (T2D)
- Non-Alcoholic Fatty Liver Disease (NAFLD)
Pathways named in the guide include short-chain fatty acid production, glucose homeostasis, insulin sensitivity, bile acid transformation and signaling, lipid metabolism, appetite and satiety regulation, barrier integrity and endotoxin exposure.
In practice: Interpret with body composition, diet, activity, metabolic and liver markers - not as a standalone metabolic result.
Gut-Heart Axis
Cardiovascular Health
Complete Microbiome AssessmentThe report looks at microbial pathways involved in the metabolism of compounds such as choline and carnitine.
What this covers
- Trimethylamine (TMA) Production
Some of these bacteria produce trimethylamine (TMA), which the liver converts to TMAO. Elevated TMAO has been associated with cardiovascular disease, metabolic dysfunction and inflammatory processes. Dietary intake plays a major role in how much TMA is actually produced.
The guide is explicit about the limit: the presence of TMA-producing bacteria does not measure TMA or TMAO concentrations, and does not establish cardiovascular risk.
In practice: Read it as microbial potential plus diet, not as a cardiac risk score.
Within the Gut-Immune Axis
Skin Health
Complete Microbiome AssessmentSkin sits inside the immune picture rather than beside it. The Complete Microbiome Assessment covers it within the Gut-Immune Axis.
What this covers
- Eczema and Atopic Dermatitis
Evidence suggests the gut microbiome influences allergic and atopic disease through regulatory T cell development, immune maturation, barrier function, inflammatory signaling and microbial metabolite production. People with eczema and atopic disease often show reduced diversity, fewer beneficial commensals and expansion of inflammation-associated organisms.
The clinical guide also discusses inflammatory skin involvement - rosacea, eczema, histamine-sensitive presentations - when choosing gentler intervention strategies.
In practice: Most useful where skin and gut symptoms move together, or where histamine sensitivity is suspected.
A flagged section does not indicate disease, diagnosis or clinical dysfunction. It highlights an area that may deserve review alongside symptoms, history, lifestyle and other laboratory findings. GutID provides wellness and educational insights and is not a diagnostic test.
A single IBS case
Tracking microbiome changes over time
Three GutID Target Plots from the same person, who came to their first test living with IBS. By the third, fourteen weeks later, they reported their symptoms had resolved. Every ring is a level of classification, from phylum at the center out to species at the edge, and every band is sized by how much of the sample that organism accounts for.
First test · living with IBS
One species is running the ecosystem
This first test was taken while living with IBS. Phocaeicola dorei alone accounts for 58.1% of the sample, and Bacteroidetes for two thirds of it. Only 59 species are drawn on the whole plot, across 36 genera.
A community this concentrated has little to fall back on if its dominant organism is disturbed.
Second test · 4 weeks on psyllium husk
The dominant wedge starts sharing
The largest species is down to 31.4% — close to half what it was. Parabacteroides distasonis and Hominimerdicola aceti now hold real territory.
The species count has barely moved, 59 to 51. What changed first was not how many organisms were present, but how evenly the space was shared.
Third test · 14 weeks on psyllium husk
No single organism dominates
The largest species is now 18.8%, and Firmicutes has overtaken Bacteroidetes. The plot draws 137 species across 89 genera, against 59 and 36 at baseline.
By this third test the individual reported their IBS symptoms had resolved.
Zoom into Firmicutes to see where the new ground went.
Hover any band to read the organism and its share. Click to zoom in, and use the trail above the chart to come back out.
What changed between these tests was a fiber recommendation: psyllium husk. No protocol, no stack, no antimicrobials. Not every case is this straightforward. The difficult part was not the intervention — it was knowing which substrate this particular ecosystem was short of, and introducing it at a pace it could take.
A single case, shown to illustrate how a Target Plot changes between tests. Percentages and counts are read from these plots. The IBS history and the symptom outcome are as reported by the individual, not measured endpoints. Individual results vary and this is not a predicted outcome. GutID provides wellness and educational insights, is not a diagnostic test, and does not diagnose or treat IBS.
What you do with it
From Microbiome Insights to Personalized Action
These are the building blocks a report points toward. Which one, and how fast, is the part that needs the data — in a highly dysbiotic gut, an aggressive prebiotic can make bloating, fermentation symptoms and intolerance worse rather than better. Gradual introduction and careful selection are usually the safer route.
Fiber supplements
Psyllium husk, PHGG, acacia fiber.
Support microbial fermentation, and the resilience and diversity of the ecosystem as a whole.
Prebiotics
Inulin, FOS, GOS.
Stimulate selected bacterial groups rather than feeding the community indiscriminately.
Polyphenols
Berry powders, green tea extract, cocoa flavanols.
Ecosystem modulation and support for the metabolites bacteria produce.
Targeted support
Resistant starch, omega-3 fatty acids, butyrate.
Used where the report points at a specific gap — resistant starch, for instance, only if it is tolerated.
For practitioners
The clinical evidence, and how practice accounts work.
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