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What it shows

What happens in your gut goes beyond digestion.

The bacteria in your gut interact with digestion, mood, immunity, metabolism and the heart. GutID reports on those patterns so you and your practitioner can choose specific foods, prebiotics and probiotics.

Five physiological systems, read from one sample.

Page 2 of a Complete sample report, listing the five gut axes, on linen beside a GutID sample tube Page 2 of a Complete sample report

The five Gut Axes

Gut function is only the beginning.

Through five gut axes (gastrointestinal, brain, immune, metabolic and heart), the molecules and immune signals your gut microbiome produces reach systems most people never connect to digestion. The Complete Microbiome Assessment reads all five. Core Gut Insights concentrates on gut function, for people whose concerns start and stay there.

A breakfast table midway through the meal: yogurt with berries, granola and walnuts
Gut–Gastrointestinal axis checklist from page 2 of a Complete sample report
From page 2 of a Complete sample report

Gut–Gastrointestinal Axis

In both reports

Gut function

The gut is where most host-microbe interaction happens. This section looks at bacterial patterns associated with digestion, barrier integrity and day-to-day digestive symptoms.

Report subcategories

  • Small Intestinal Bacterial Overgrowth (SIBO)
  • Inflammatory Bowel Disease (IBD)
  • Bile Acid Metabolism

In practiceA flag means patterns reported more often in people with digestive dysfunction are present. Read it against symptoms, history and other results, never on its own.

What this covers

The GutID Clinician Guide lists what the gut microbiome contributes here: digestion and fermentation of dietary substrates, nutrient absorption, maintenance of intestinal barrier integrity, regulation of mucosal immunity, production of microbial metabolites, and protection against pathogen colonization.

Core Gut Insights is built around this area, so if your concerns are digestive, IBS included, that report covers it. It is in the Complete Microbiome Assessment too, which also lists IBS under the Gut–Brain Axis.

A man reading in an armchair by lamplight
Gut–Brain axis checklist from page 2 of a Complete sample report
From page 2 of a Complete sample report

Gut–Brain Axis

In the Complete Microbiome Assessment

Mental health

Gut and brain exchange signals constantly, through nerves, immune signaling and the molecules bacteria produce.

Report subcategories

  • Mood Disorders
  • Irritable Bowel Syndrome (IBS)
  • Alzheimer’s Disease (AD) Risk
  • Parkinson’s Disease (PD) Risk

In practiceUseful where digestive and mood symptoms occur together, which is common and is usually handled as two separate problems.

What this covers

The report evaluates bacterial species associated with neurological, behavioral and neuroimmune signaling, including pathways involving GABA, serotonin, dopamine and norepinephrine.

These findings do not diagnose neurological disease and are not evidence that a person has, or will develop, a particular disorder.

A father sharing an orange with his young daughter on a picnic blanket
Gut–Immune axis checklist from page 2 of a Complete sample report
From page 2 of a Complete sample report

Gut–Immune Axis

In the Complete Microbiome Assessment

Immune health

Roughly 70 to 80% of the body’s immune cells sit within or close to the gastrointestinal tract, so the bacteria there are in constant conversation with the immune system.

Report subcategories

  • Lipopolysaccharide (LPS) Production
  • Histamine Production
  • Eczema and Atopic Dermatitis

In practiceInterpret alongside allergic history, autoimmune conditions and inflammatory markers.

What this covers

The microbiome contributes to immune system maturation, development of immune tolerance, regulation of inflammatory responses, barrier integrity, host defense, and the balance of regulatory and pro-inflammatory pathways.

Alterations have been associated with allergic disease, autoimmune conditions and chronic inflammatory disorders.

Within the Gut–Immune Axis

Skin health

The report reads skin as part of the immune picture. The Complete Microbiome Assessment covers it within the Gut–Immune Axis.

Report subcategories

  • Eczema and Atopic Dermatitis

In practiceMost useful where skin and gut symptoms move together, or where histamine sensitivity is suspected.

What this covers

Evidence suggests the gut microbiome influences allergic and atopic disease through regulatory T-cell development, immune maturation, barrier function, inflammatory signaling and microbial metabolite production. People with eczema and atopic disease often show reduced diversity, fewer beneficial commensals and expansion of inflammation-associated organisms.

The Clinician Guide also discusses inflammatory skin involvement, such as rosacea, eczema and histamine-sensitive presentations, when choosing gentler intervention strategies.

A woman on a morning run along a tree-lined park path
Gut–Metabolism axis checklist from page 2 of a Complete sample report
From page 2 of a Complete sample report

Gut–Metabolism Axis

In the Complete Microbiome Assessment

Metabolic health

Gut bacteria sit inside the pathways that govern blood sugar, fat storage, appetite and inflammatory load.

Report subcategories

  • Obesity
  • Type 2 Diabetes (T2D)
  • Non-Alcoholic Fatty Liver Disease (NAFLD)

In practiceInterpret with body composition, diet, activity, metabolic and liver markers, not as a standalone metabolic result.

What this covers

Pathways named in the Clinician Guide include short-chain fatty acid production, glucose homeostasis, insulin sensitivity, bile acid transformation and signaling, lipid metabolism, appetite and satiety regulation, barrier integrity and endotoxin exposure.

A woman laughing on a misty lakeside trail
Gut–Heart axis checklist from page 2 of a Complete sample report
From page 2 of a Complete sample report

Gut–Heart Axis

In the Complete Microbiome Assessment

Cardiovascular health

The report looks at microbial pathways involved in the metabolism of compounds such as choline and carnitine.

Report subcategories

  • Trimethylamine (TMA) Production

In practiceRead it as microbial potential plus diet, not as a cardiac risk score.

What this covers

Some of these bacteria produce trimethylamine (TMA), which the liver converts to TMAO. Elevated TMAO has been associated with cardiovascular disease, metabolic dysfunction and inflammatory processes. Diet plays a major role in how much TMA is produced.

The Clinician Guide is explicit about the limit: the presence of TMA-producing bacteria does not measure TMA or TMAO concentrations, and does not establish cardiovascular risk.

GutID provides wellness and educational insights and is not a diagnostic test. A report finding is a pattern in the bacterial community, read alongside symptoms, history and other results.

A single IBS case

Tracking microbiome changes over time

Target Plots from the same person. The first test was taken while living with IBS; the third came 14 weeks later, when they reported their symptoms had resolved. Each ring is a level of classification, from phylum at the center out to species at the edge, and each band is sized by how much of the sample that organism accounts for.

Interactive GutID Target Plot showing the bacterial community as nested rings, from phylum at the center to species at the edge

First test · living with IBS

One species is running the ecosystem

This first test was taken while living with IBS. Phocaeicola dorei alone accounts for 58.1% of the sample, and Bacteroidetes for two-thirds of it. Only 59 species are drawn on the whole plot, across 36 genera.

A community this concentrated has little to fall back on if its dominant organism is disturbed.

Third test · 14 weeks on psyllium husk

No single organism dominates

The largest species is now 18.8%, and Firmicutes has overtaken Bacteroidetes. The plot draws 137 species across 89 genera, against 59 and 36 at baseline.

By this third test the individual reported their IBS symptoms had resolved.

Zoom into Firmicutes to see which groups expanded.

Hover or tap any band to read the organism and its share. Select one to zoom in, and use the trail under the chart to come back out. With a keyboard: the arrow keys move between bands, Enter zooms in and Escape zooms out.

What changed between the testsThe one change between these tests was a fiber recommendation: psyllium husk, chosen because this ecosystem was short of the substrate it provides, and introduced at a pace it could tolerate. Not every case is this straightforward.

A single case, shown to illustrate how a Target Plot changes between tests. Percentages and counts are read from these plots. The IBS history and the symptom outcome are as reported by the individual, not measured endpoints. Individual results vary and this is not a predicted outcome. GutID provides wellness and educational insights, is not a diagnostic test, and does not diagnose or treat IBS.

What you do with it

From microbiome insights to personalized action.

The report’s data helps decide which of these fits, and how fast to introduce it. In a highly dysbiotic gut, an aggressive prebiotic can make bloating, fermentation symptoms and intolerance worse, so gradual introduction and careful selection are usually the safer route.

See the evidence behind it

Fiber supplements

Psyllium husk, PHGG, acacia fiber

Support microbial fermentation, and the resilience and diversity of the ecosystem as a whole.

Prebiotics

Inulin, FOS, GOS

Stimulate selected bacterial groups rather than feeding the community indiscriminately.

Polyphenols

Berry powders, green tea extract, cocoa flavanols

Shift the balance of the community, and support the metabolites bacteria produce.

Targeted support

Resistant starch, omega-3 fatty acids, butyrate

Used where the report points at a specific gap. Resistant starch, for instance, only if it is tolerated.

See it in your own report.

Core Gut Insights reads gut function. The Complete Microbiome Assessment reads all five axes, from one at-home sample.

For practitioners: see how GutID works in clinical practice

A GutID report open on a laptop